Journal article
Morning exercise mitigates the impact of prolonged sitting on cerebral blood flow in older adults
MJ Wheeler, DW Dunstan, B Smith, KJ Smith, A Scheer, J Lewis, LH Naylor, I Heinonen, KA Ellis, E Cerin, PN Ainslie, DJ Green
Journal of Applied Physiology | AMER PHYSIOLOGICAL SOC | Published : 2019
Abstract
Preventing declines in cerebral blood flow is important for maintaining optimal brain health with aging. We compared the effects of a morning bout of moderate-intensity exercise, with and without subsequent light-intensity walking breaks from sitting, on cerebral blood velocity over 8 h in older adults. In a randomized crossover trial, overweight/obese older adults (n 12, 70 7 yr; 30.4 4.3 kg/m2), completed three acute conditions (6-day washout); SIT: prolonged sitting (8 h, control); EXSIT: sitting (1 h), moderate-intensity walking (30 min), followed by uninterrupted sitting (6.5 h); and EX BR: sitting (1 h), moderate-intensity walking (30 min), followed by sitting (6.5 h) interrupted with ..
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Awarded by Agricultural Research Council
Funding Acknowledgements
This work was funded by a project grant from the National Health and Medical Research Council (NHMRC) of Australia (1062338). M. J. Wheeler was supported by the University of Western Australia and the Baker Heart and Diabetes Institute. D. W. Dunstan was supported by a NHMRC Senior Research Fellowship (NHMRC APP1078360). I. Heinonen was supported by the University of Turku, Hospital District of South-West Finland and the Juho Vainio Foundation. E. Cerin was supported by an Australin Research Council Future Fellowship (ARC FT140100085). P. N. Ainslie was supported by a Canadian Research Chair. D. J. Green was supported a NHMRC Principal Research Fellowship (APP1080914).